A new study demonstrates that using pulsed magnetic fields (PEMF) signals accelerates the physiological processes involved in wound healing.

Researchers at the Montefiore Medical Center (New York, NY, USA) conducted a prospective, placebo-controlled and double-blinded study of 100 rats, each with a linear skin incision on their dorsum that was subsequently sutured and treated with non-invasive PEMF signals. Four different signals were used targeting the calcium/calmodulin pathway, which is at the start of the anti-inflammatory and growth factor stages of tissue repair (PEMF has been shown to accelerate the binding of calcium to calmodulin).

The results showed that at the end of the 21 day period, one specific signal had the most significant effect on wound repair, demonstrating a 59% increase in wound tensile strength compared to control, leading researchers to conclude that exposing wounds to PEMF of very specific configurations accelerated wound repair in the early, most critical phases of healing in this animal model. The pulsed magnetic devices used in the study were developed by Ivivi Technologies (Northvale, NJ, USA). The study was published in the August 2007 edition of Plastic and Reconstructive Surgery.

“As we get a clearer picture of the transduction properties of the physiological pathways involved in tissue repair, we can configure new PEMF signals,” said co-author Dr. Arthur Pilla, a professor of biomedical engineering at Columbia University and science director of Ivivi Technologies. “We are increasingly able to fine-tune the configuration of PEMF signals to achieve a more optimal 'dose’ for different indications, as evidenced in this study.”

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